Eukaryotic replication origins are 'licensed' for replication early in the cell cycle by loading Mcm(2–7) proteins. As chromatin replicates, Mcm(2–7) are removed, thus preventing the origin from ...
The chromosomes align along the metaphase plate. As in mitosis metaphase, (and unlike meiosis metaphase I), fibers from the centrioles begin to pull on each one of the chromosomes from both directions ...
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