The cerebral cortex, the brain's outermost region responsible for higher cognitive functions, depends on a highly ordered, layered structure. Its proper development requires newly generated neurons to ...

Medical University of South Carolina scientists report in Neuron that they have uncovered a way to restore an opioid-weakened brain pathway in a preclinical model. The MUSC research team, led by ...

BOSTON, Mass. (July 15, 2024)—A groundbreaking study conducted at the lab of Beth Stevens, PhD, at Boston Children’s Hospital has revealed that an immune protein impacts neuronal protein synthesis in ...

A team of researchers from the University of Massachusetts Amherst is the first to show how proteins called "chaperones" are vital in ensuring that neurons can transmit signals to one another. When ...

The brain is probably the least explored organ, much of which is due to the difficulty of studying it in situ rather than in slices under a microscope. Even growing small organoids out of neurons ...

A new Yale study has revealed that neurons — the energy-hungry cells that connect and direct activity in the brain — are equipped with “backup batteries” that kick in to keep the brain running during ...

A new McGill University study has found a direct link between age-related declines in neuron activity in the cerebellum and ...

In many ways, the brain is uncharted territory akin to the deepest parts of the ocean and farthest reaches of outer space. As with any new frontier, navigating it requires a map. Researchers have ...

A clearance mechanism involving microglia has been known to relieve neurons of toxic protein aggregates such as those associated with Alzheimer’s disease and Parkinson’s disease. Unfortunately, this ...

Scientists have shown that specialized cells involved in how the body responds to insulin are activated in the brain after exercise, suggesting that physical activity may directly improve brain ...