TCTMD

Many PFO Closure Patients May Be Treated Off-label

The population of patients undergoing patent foramen ovale (PFO) closure in the US doesn’t match those of the clinical trials that formed the basis of the US Food and Drug Administration’s approval of ...
Medscape

Poststroke PFO Closure Helps Some, But Not All, Younger Adults

Patent foramen ovale (PFO) closure reduced the risk for recurrent ischemic stroke in most young and middle-aged adults with cryptogenic stroke but increased the risk for atrial fibrillation (AF) in a ...
TCTMD

TCT 112: The Association Between Residual Shunt and the Endothelialization of the Closure Devices for Patent Foramen Ovale (PFO) 12 Months After Implantation Evaluated by ...

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The New England Journal of Medicine

Long-Term Outcomes of Patent Foramen Ovale Closure or Medical Therapy after Stroke

Whether closure of a patent foramen ovale reduces the risk of recurrence of ischemic stroke in patients who have had a cryptogenic ischemic stroke is unknown. In a multicenter, randomized, open-label ...