The 49ers lost a large contingent of household names that helped them dominate the NFC for the last five-plus years, ...

Sam Darnold entered the year as the San Francisco 49ers' new backup quarterback after five unfruitful seasons with the New ...

Juszczyk had been with the 49ers for the last eight years and is a nine-time Pro Bowler with one first-team All-Pro selection ...

Quick take: The 49ers must have big plans for the draft after failing to add a premier edge rusher in the opening week of ...

The San Francisco 49ers will have some work to do finding replacements for 9 starters they lost from their depth chart this ...

The San Francisco 49ers cut defensive linemen Javon Hargrave and Maliek Collins at the start of the new league year in the ...

The 49ers have streamlined their roster and finances with the aim of extending Brock Purdy. Now all he’s got to do is win a ...

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After losing multiple veterans as free agents, the question of what's next for the 49ers is difficult to answer.

Quarterback Mac Jones signed a two-year deal with the 49ers, who chose to draft Trey Lance with the third pick in 2021.

Brandon Staley coached Isaac Yiadom on the 49ers, and now they're together again on the Saints. Yiadom had his best years in ...

Long snapper Jon Weeks has spent his entire career in Houston, playing 15 seasons for the Texans. He left Thursday, signing a ...